Rates of anxiety, depression, insomnia, opioid overdose, and suicide have been climbing during this pandemic. Clearly, the mental health of many is suffering. Botanicals, along with sensible recommendations for lifestyle and counseling, can be highly effective for improving mental and emotional well-being. Using case studies, clinical experience, historical use, and contemporary science, this presentation will explore various treatment protocols for mental health issues including anxiety, depression, and burnout.